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ACS Infect Dis ; 7(6): 1369-1388, 2021 06 11.
Article in English | MEDLINE | ID: covidwho-1493010

ABSTRACT

The SARS-CoV-2 outbreak that emerged at the end of 2019 has affected more than 58 million people with more than 1.38 million deaths and has had an incalculable impact on the world . Extensive prevention and treatment measures have been implemented since the pandemic. In this Review, we summarize current understanding on the source, transmission characteristics, and pathogenic mechanism of SARS-CoV-2. We also detail the recent development of diagnostic methods and potential treatment strategies of COVID-19 with focus on the ongoing clinical trials of antibodies, vaccines, and inhibitors for combating the emerging coronavirus.


Subject(s)
COVID-19 , Vaccines , Humans , Pandemics , SARS-CoV-2
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